Anima Mundi Herbals
MITRAGYNIA speciosa - Red Kali
Mitragyna speciosa, well known as "Kratom", is a tropical evergreen tree in the coffee family (Rubiaceace). Depending on the strain and quantity used, it can either be euphoric/stimulating, or more sedating. The wildcrafted strain that we are carrying for a limited time comes from a beautiful farm of older growth trees in Indonesia. The strain is known as 'Red Kali' which can be an excellent solution for pain management and deep relaxation.
"Kratom" has become famous for its ability to treat chronic pain, digestive ailments, mood imbalances, depressive tendencies, and as an aid for opiate withdrawal.
Smoked, chewed or steeped in tea, Kratom has a long history as a folk remedy for diarrhea, muscle pain, fever, coughing, hypertension, fatigue, depression, and other ailments. In modern times it has been used to treat opiate withdrawal, anxiety, chronic pain, and to boost the endurance of manual laborers. Despite its proscribed status in several countries, Kratom is still consumed socially during community gatherings in the Asian tropics.
The main active ingredients of kratom are the alkaloids mitragynine and 7-hydroxymitragynine. There is evidence that these alkaloids can have analgesic (pain relieving), anti-inflammatory, or muscle relaxant effects. For this reason, kratom is often used to ease symptoms of fibromyalgia.
STIMULANT EFFECTS | According to the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), a small dose that produces stimulant effects is just a few grams. The effects usually happen within 10 minutes after ingesting it and can last up to 1 1/2 hours. These effects can include: alertness, sociability, giddiness, reduced motor coordination
SEDATIVE EFFECTS | A larger dose of between 10 and 25 grams of dried leaves can have a sedative effect, with feelings of calmness and euphoria. This could last for up to six hours.
NOT YOUR TYPICAL PAINKILLER | At least 25 alkaloids have been isolated from Kratom leaves. Three of these compounds directly activate opiate receptors. Mitragynine (MG), the dominant indole alkaloid found in Kratom, is responsible for much of Kratom’s analgesic activity. MG’s painkilling potency is equal to codeine. Japanese researchers reported in 2004 that MG accounted for 66 percent of a crude Kratom extract and six percent of plant material by dry weight.
It’s worth noting that pure, single-molecule MG is actually less effective as a painkiller when compared to equal amounts of MG in a whole plant Kratom extract, which contains many biologically active components, including 7-hydroxymitragynine (7-OH-MG). A potent analgesic, this compound has a high affinity for the mu-opioid receptor, but it is structurally different from other opioids. MGs don’t bind to opiate receptors like an ordinary opiate. What’s more, these promising medicinal compounds can confer novel, beneficial effects that differ from those of pharmaceutical opioids.
Preclinical research has determined that Kratom’s physiological properties are mediated by several neurotransmitter systems—dopamine, serotonin, GABA—in addition to its unique interactions at the opioid receptors. But MG’s painkilling activity does not directly involve the cannabinoid CB1 receptor, according to a 2012 study by Malaysian scientists.
Much like aspirin, Kratom produces an anti-inflammatory effect by suppressing prostaglandin production in the COX-2 pathway. Cannabidiol (CBD), a potent anti-inflammatory, works through similar channels. Could Kratom be the CBD of the opiate world?
Reported side effects of long-term use of kratom include: potential addiction, constipation, nausea, lack or loss of appetite, severe weight loss, insomnia.
LEGALITIES | The unauthorized use of this herb has spread to Western societies in recent years, much to the chagrin of the DEA and the Food and Drug Administration (FDA) officials who view Kratom as a threat to public health. On August 25, 2016, the DEA announced its intention to add Kratom to the list of illegal Schedule I drugs. Yet due to the huge amount of claims and disputes of hundreds of thousands of people in the US, the made it legal for sale due to the incredible amounts of help and healing its brought to many getting off of opiate’s or seeking an alternative solution to pain killers.
For an excellent overview on its toxicology, history, use and a bit on its history with FDA and the DEA. Continue reading here.
*This product is not intended to diagnose, treat, cure, or prevent any disease. ... These statements have not been evaluated by the Food and Drug Administration.
INGREDIENTS: Mitragynia speciosa, strain: Red Kali
AMOUNT: 4oz powder